Peripheral Neuropathy Vitamin B6 Toxicity

Dave Hi, everyone. Its Dave Asprey with Bulletproof Radio. Todays cool fact of the day is that its no secret I love fat but theres new research that says even high fat diets can be brain protective. The theory behind this research is that fat particularly mediumchain triglycerides gives the brain enough energy to trigger selfrepair, the idea that your brain cells like ketones especially the neurons, that it may give them the ability to repair themselves more. We dont know this for sure. Its just intriguing research but its cool. Todays episode is one of my favorite kinds and one of your favorite.

Kinds too because its a Q and A episode. We get so many questions in online and I dont do these as often as I would like because I really like the opportunity to do them in person with someone else rather than over Skype. If youre watching this live, you probably noticed that Im not in my normal studio. Thats because Im here at Tampa at JJ Virgins Mindshare event. She brings together about a hundred successful health influencers, people who are working to make everyone around us healthier. Im honored to be here but it gave me an excuse to hang out with my buddy,.

Zak. Zak is going to run through a bunch of your questions that youve submitted on Facebook, on YouTube and on our blog posts just at the very bottom of the blog. If its a podcast blog, theres a form that you can use to submit questions. If youre listening to this and you want to get one of your questions answered, submit it there and we track these things. Then, every time Zak and I sit down together, we go through and Ill answer them for you to the best of my ability. All right, Zak. Lets do it, man.

Bulletproof Radio QA 191

Zak All right. Our first question comes from Bodjie. He says, Hi, Dave. Ive been using your products for the last six months now. I just want to ask what is the difference between MCT oil, XCT oil and brain octane Dave This is a thinly veiled This is actually a question from someone This isnt like a marketing question Zak Actually, we got a bunch of the same questions. People want to know. Dave Good. MCTs are, if you look at this from a marketing perspective, theres four kinds of MCTs. The coconut oil companies will say, Oh, look. This is 62 MCT, but.

Theyre lying to you because the richest socalled MCT thats in coconut oil is called lauric acid. Its the predominant fatty acid like that. In coconut oil, theres just one problem. It doesnt get processed by the liver like a mediumchain triglyceride. It gets processed like a longchain triglyceride. You can get away with selling lauric acid as a mediumchain triglyceride even though its a lie. Its not a mediumchain triglyceride. It doesnt work that way. Now, lauric acids good for you but its dirt cheap. Its called eat coconut oil because half of coconut oil is lauric acid. I recommend eating coconut.

Oil as a way to get that one MCT. Theres four kinds of MCTs that different companies will try and sell us as real MCT just like coconut oil companies but youre not getting the purest stuff that were using from metabolic activation. Now, thats plain MCT. Theres also problems with just normal commodity MCT that had to do with something called C17. I wrote about this in the Bulletproof Diet book. C17 is an odd chain fat thats made by less pure processes. If youve ever had severe disaster pants after using commodity MCT, theres a reason for that. Some of.

It comes from cosmetic machines. Some of its imported from China but most of it has the C17 which causes the gastro distress. It happens. You get much less of that from XCT oil. Now, XCT oil is the two shortest lengths. Its not all four of the MCTs. Its just two of them. Its the C8 and the C10. XCT oil which we usually call the upgraded MCT oil, that stuff is distilled an extra time more than normal MCTs that youd find on the market. Its that extra step of distillation and filtering that gets rid of the C17 and.

The other contaminants so it doesnt have the same level of GI distress or disaster pants becomes much less of an issue. XCT oil is more affordable because it has the C8 and the C10. That means you can afford to have it. Its roughly six times stronger than coconut oil. When you look at the GI distress though, it is harder on the stomach than pure C8 which is our brain octane oil. Brain octane oil is about 6 of whats in coconut oil. Brain octane goes to energy fastest.

In the body. When you take that stuff, you feel it up here first. Its literally octane for your brain. When you take XCT oil, you still get some of the C8 which goes to the brain quickly. The C10 takes more time to get in. You dont get as big of a boost but it still works. Compared to putting, say, coconut oil which is what you put in just plain butter coffee thats not Bulletproof coffee, youre getting 6 brain octane oil on that. Thats why theres such a big difference between in the book I read about heres how to make.

A commodity butter coffee. You can throw whatever you want in there and you can get some benefit. If you put any fat, even corn oil which I seriously dont recommend, if you put that in your coffee and you blend it up, its not going to taste that good for one thing but at least youre not binding the antioxidants. Coffee had these polyphenols and catechins. These things are important for your health. If you put milk in there, the protein from the milk sticks to them and then you dont.

Get them. There are studies that show a 340 reduction in antioxidants that are bioavailable just by adding milk. Any kind of fat would be an improvement including just coconut oil, including even nonorganic like cornfed butter. Thats not anywhere near Bulletproof. Bulletproof is brain octane or XCT oil, grassfed butter which preferably is cultured and unsalted. The culturing helps to reduce casein even more and then you add in this XCT or brain octane. Thats what gives you like, Wow, something just happened in my day. Hopefully, thats a good difference.

Zak Yeah. When you talk about people that are making a decision about I want to get XCT or brain octane, what are the tangible benefits from a physiological standpoint that they can expect Dave You get faster and more for your brain when youre doing C8 versus C10 but you save a few dollars. One of the things thats really important to me, I dont think high performances is for rich people. I am willing to invest more. I always have been even when I was living paycheck to paycheck which I had for a lot longer than Id like to have.

Been, I would prioritize my health. I had spent money on the things that made me perform well and feel good because its a longterm investment. You can put a little bit in now or you can pay your cardiac surgeon later. I do my best to make things affordable. Both of those things will work for Bulletproof coffee and you feel different than if you have coconut oil or youre putting in a bunch of lauric acid and thinking youre getting the benefits of a mediumchain triglyceride. Youre not. Eat some coconut oil. Get some lauric acid because lauric acid has some antimicrobial.

Effects. Its a good thing. Its not just a mediumchain in the technical definition of what mediumchains do. If it goes through liver, its not mediumchain the way were using it for biohacking. Zak Fair enough. The next question comes from John. He says, Dave, Im interested in hearing your thoughts on chiropractic work. This seems to be one of the most popular yet least associated biohacks and has a good deal of promotion and criticism for its health benefits. Your opinion on chiropractic Dave Chiropractic is like doctors. Our doctors go to doctors then. I don’t know. Which doctor.

Are we talking about The school or the study of chiropractic care is such a broad spectrum. I know chiropractors who are basically practicing antiaging stuff. I know others or maybe I wouldnt want to go there because theyre really aggressive in their treatments. Ive had profound benefits from chiropractic work. I know countless other people who have. That said, to say that this enormous body of study is good or bad is incredibly simplistic. There are amazing chiropractors who are very quantitative in their analysis. There are others who frankly probably arent helping. The same is true if you go into any medical.

Clinic of any kind of medicine. I would never say I think that the entire study of chiropractic is useless. Its not. Now, one of the things that I find really interesting is that you can take a very, very sensitive basically thermometer and you can run it down the spine. This is a relatively old thing you could do as a chiropractor. When you run it down the spine, what they call subluxations, areas where the spine is aligned properly, youll actually get a small, like a.1 or.2 degree Fahrenheit difference between those vertebra.

And the other ones. Funny, those are the same ones theyll find with their fingers. Why is there heat there Some things may be happening but then you go in a little bit more and you say, All right, maybe you dont need to do any work there. Maybe you do. What would tell us whether it works You could do clinical studies. There are clinical studies that show chiropractic works. There are also some that show it doesnt work. I might add that it could be a question of the patient. It could be a question of the chiropractor. It could be a question for.

Diagnosis. It could be a question of the study authors but Ive seen huge benefits. In fact, one of the things that was most profound, when my son Alan was born, he was for the first five days of life, he had a rough time. It was pretty tight coming out. Apparently, that happens when youre born. He would sit there and he lay on his back. Hed only sleep for 20 minutes. His right shoulder was up and he was a little bit like the right side of his face was scrunched a little bit. He looked like he was in pain.

It just so happens that one of my friends, one of my our family friends is a guy named Dr. Peter Fish. Dr. Fish has lectured at medical schools around the world. Hes a pediatric chiropractor. Hes gone around and hes taught doctors in ICUs for infants how to raise oxygen levels in babies by basically lightly, lightly touching this spot on the back of their neck because they have this little crick in their neck that lowers their oxygen levels. This is biohacking. In fact, Dr. Fish used to be a computer programmer before he got.

Into chiropractic. I loved the guy. Dr. Fish, if youre watching, kudos man. Anyhow, Alans there. Dr. Fish put his hand behind Alans right shoulder, just barely touched it, the lightest touch. Literally, Alan melted into the table and he slept for eight hours straight. He stopped moving that weird way. He stopped crying. Ive seen this happen. Ive had adjustments myself that were enormously useful. If you watched the podcast with Jeff Spencer, Jeff is basically the team doctor for multiple Tour de France teams where he keeps them healthy. Hes also a chiropractor. He gave me an.

Adjustment because something happened at the Bulletproof Conference where something was wrong with my back. He fixed it. It wont fix everything. I dont think chiropractic care is that likely to fix a broken bone or a tumor but can it functionally help you Hell, yeah. Its okay to be skeptical of anything. You should be skeptical of any healthcare provider until you see their track record and their abilities and you see if it works but to throw out that entire school of medicine because youre skeptical, youre not doing.

Yourself any favors. Zak Good answer. My personal experience with chiropractic is very quantitative. My doctor in Portland, Dr. Guthrie who youve been adjusted, right, she actually does all those tests like the thermometer on your back, checks your posture. They measure your feet to see how your arches are. They actually do an HRV test also. Then, I get those done every three months to track the progress. I can point to the data for myself that its really improved over the times that Ive been doing it. I cant say enough good things about.

Chiropractic if you have the right doctor. The next question comes from Beth. She says, I have a copper IUD and Im curious what birth control is the most Bulletproof Dave Wow. Some people dont know that in the first book that I worked on with my wife Dr. Lana, the fertility specialist was a book on fertility. Its The Better Baby Book. The best birth control you could possibly have is learn when youre ovulating. Learn when youre going to ovulate. There are very predictable changes in the female body.

You can look at mucus. You can look at changes in temperature. There are various apps. Theres calendars. If youre in tune with your body, you will know this. Heres a weird little trick. If you sleep in a blackout room the way I recommend, if when the moon is full, you open the curtain and that night, you dont get that much sleep with the full moon because youre going to lighten your window but your body will start to synchronize your cycles with moon the way they would have if you lived in a cave. That can actually help you predict.

When youre going to ovulate. If you know youre going to ovulate, the simple thing to do is use a condom around that time or just avoid having sex when youre ovulating. Thats hard to do because when youre ovulating, youre actually horny. Also, men around you know youre ovulating through subtle biological signals like pheromones and then we keep trying to have sex with you. I would rely on the backup method during that time. Now, what about IUDs I think IUDs, theres a case for them but IUDs also can trigger.

Some autoimmunity in some cases and theres some cancer risks. I would look very carefully at the research behind the one youre looking at using to see what studies have been done and how long has it been used and what are the risk factors that go with it. There can also be clotting things and IUDs can get lost but they can be a safe method of birth control. They can also be better for you a lot better than the birth control pill. I will tell you flat out, if youre on a birth control pill, you should get off of the birth control pill.

For your health, for your breast cancer risk, especially your breast cancer risk. The other thing thats just terrible, if youre taking the birth control pill, it influences your ability to smell a good prospective mate. It sounds a bit weird but theres good science behind this. We use pheromones. Basically, youll choose a mate whos biologically more likely to be compatible with you based on how he smells. If you take the pill, you cant smell a proper biological match. This actually happens where youre on the pill, you meet someone.

You fall in love. You get married. You decide to have kids. You go off the pill and suddenly, the person you married doesnt smell right. Youre not physically attracted to them anymore. This is the nittygritty of biohacking. The pill not only raises your cancer risks substantially. It also means that youre less likely to pick the right person. From a health perspective, allow your body to do what its supposed to do, become aware of it and then be extra careful with the backup method like a condom or a condom and even a spermicide. There can be risks from spermicides.

You dont want those inside you all the time but if its the time of life where you dont want to get pregnant. Okay, fine. Do that but to take a pill every day or to use an IUD if its an IUD that is one and there are many that are associated with problems, you should watch out for that. There are a few other methods you can use. Basically, some of those things are Man, Im blanking on it. This is the end of a long day. The ring that goes over your cervix,.

The diaphragm. No one I know actually has ever used the diaphragm but you read about these things. Apparently, the diaphragm, from the studies that I read during the creation of The Better Baby Book, the diaphragm is a safe and an effective and actually quite useful and good method of birth control but not one thats that widely used anymore. That may be something thats worth investigating. Whether a diaphragm or an IUD is better, I don’t know because I havent seen any studies that say that. There might have been something.

In the last three years since I put together The Better Baby Book thats changed but I would lean as far away from the pill as I could and lean more towards what I suppose you could call the rhythm method but its not a rhythm. Its the biohacker method. Whats going on with my body, am I about to ovulate, am I expecting it to happen, things like that and thats pretty safe. If its in that week when it might happen, use a condom. You totally go with it and youre safe.

Zak This next question is about protein. Its from Jonathan. He says, Dave, I recently have been using the Bulletproof grassfed collagen protein and I noticed that the actual grams of protein per serving were only 7 grams per serving. Ive always been told that in order to put on a lot more muscle weight, one needs to consume around 25 grams of protein per serving three times a day. Is this true Also, he suffers from chronic tendonitis and was wondering if collagen protein is a good choice over other proteins for his joints.

Dave Serving size is something thats entirely variable. I went with 7 grams because thats a tablespoon. If you want 25 grams, lets see, seven times four is 28 grams. You basically use four tablespoons. It could have easily said serving size is four tablespoons but then people want less. If youre bigger, you eat more protein. If youre smaller, you eat less protein. If you want to get the benefits of using collagen for skin hydration and collagen for allowing better electrical flow through well hydrated skin as well as joints support and things.

Like that, even 7 grams a day will do that for you. You can basically take a spoon of collagen and put it in your coffee. You can put it in soup. You can basically It will disappear in any hot dish. Thats the way a lot of people use it. If youre using it specific as a protein source which I certainly do, if Im going to do it, Ill do 30 grams because I weigh a little bit more than 200 pounds and Ive got a lot of muscle.

The idea there is I want to support that. Collagens interesting because its high in glycine but its low in cysteine and methionine and some of the other things. You get too much cysteine like you would if you consume a lot of whey protein more than the two tablespoons a day I recommend even of upgraded whey, that can trigger inflammation. One of the reasons the BF Bulletproof Diet is a moderate protein diet is that excessive protein triggers inflammation. Proteins a crappy way for you to get energy. You shouldnt.

Be metabolizing protein for energy. You should be metabolizing protein as a building block and you should be bringing fat and even starch or carbs to get energy for yourselves. Beta oxidation of protein generates ammonia and excess biological burden. It just doesnt serve you. Then, that goes back to your question. How many grams of protein do you need in order to build muscle The short answer to that is enough. You can do this by testing. In the Bulletproof Diet book, I actually published a range of things. You want to eat the minimum.

Amount of the least inflammatory protein that it takes for you to put on the muscle you want. Dont make the mistake a lot of bodybuilders will do by just cranking up the whey because of the cysteine problem. Whey can be really irritating to the gut. I would say use good quality animal protein like grassfed meats. Use eggs and yeah, use collagen protein and use it intelligently. That would mean that just crank up your protein. Do the workouts. See what works. I think you can get there but start with the guidelines in the book.

Zak Cool. I recently made a bone broth just last weekend with some grassfed bones I had. Thats really great. I love that but it takes 12 hours if you got to do the whole thing. Most of the time, Ill just put a scoop of the collagen protein and then its like Its a nice little hack. Dave I also want to call it instant bone broth but heres the thing. Bone broth, when you make it, its broken down by heat. Youre getting good quality gelatin in bone.

Broth. Youre also getting the minerals from the bones which are not as present in the collagen protein that we make. Ive created collagen that was processed by enzymes so its broken down. Its not broken down by heat or acid like a typical gelatin would be. Its actually seven different cycles of enzymes that we use on it. When you get that, it doesnt require digestion. Bone broth is also broken down so its very easily absorbed. Its like juicing a cow when you think about it. Its very interesting to think of what happens if you make bone.

Broth to get the minerals and just the goodness of it but then you add collagen to it and I Thats actually what I do when I make bone broth is like a double down on the collagen because if thats what youre having, you want to be able to do that. Zak You get more protein that way and all the benefits and minerals. Nice. The next question is from just K. She asked Dave Like OG or some of Zak She or he asks, Can you talk more about the benefits of water with Himalayan.

Salt in the morning Dave I love Himalayan salt in water in the morning. I first heard about this through Jim Wilsons Hes wrote a very old book on adrenals. In fact, hes one of the first guys to point out adrenal fatigue. Its all the rage now. Alan Christiansons book just came out, The Adrenal Reset Diet. The first guy to really say, Oh, its the adrenals, was Jim Wilson going back almost 15 years. He talked about doing this as a way of healing adrenal fatigue. What I started doing was using it as a way to prevent adrenal.

Fatigue and to have more energy during the day and found out from that that its actually also an aerobatic thing thats been done for quite a while by some herbalists particularly going back into India. What you do is you put about a teaspoon, sometimes more, sometimes less, enough that you dont get disaster pants. You put it in water and you drink it as soon as you wake up. It sounds a little bit gross but its not. Its energizing. The reason for this is as youre working to wake up in the morning, theres this.

Circadian, I don’t know, spike in your cortisol. The reason for this is really important. When its time to get out of bed, if you dont have enough cortisols for your blood pressure, if youre going to stand up When you stand up, your blood pressure changes. Youll pass out. When you pass out, you could hit your head and then a tiger could eat you. Since this is bad for your ability to reproduce the species, your body is like, This is kind of an emergency because youre getting.

Out of bed so Im going to do what I need to do to change my sodium potassium ratio by generating more cortisol. If it needed to make enough cortisol to raise sodium and drop potassium, what if you just step in and kindly help your body by increasing sodium so that your body can balance sodium and potassium more effectively Thats the idea behind this. Many, many people whove heard about this on Bulletproof are like, I feel noticeably more energy throughout the day That was my experience when I started doing that as.

Well. Zak Personally, I noticed a difference. I just take I have a little thing of salt next to my bed. I just take a small amount and wash it with water. I dont mix it water. Personally, I dont like the taste of it. Dave Still good. Zak Just as good or Dave If youre really into the salt thing, everyone knows to make sole, which is when you take a crystal, preferably one thats been properly massaged and you put it in a bowl. The bowl has to be special bowl. You let the water percolate the salt. Then, you.

Take two teaspoons of the saltwater and you mix it with water. Seriously, this is in the book. Im not joking on salt. I tried it. It did seem to work. In fact, its interesting. You get two pinches of salt. Tossing it into your mouth and throw it down but sometimes, that brings it through a little bit, the salt. What do I do Thats what I do. I take a pinch of salt in the morning. I put it in my mouth and I just wash it down too because.

Its just easier but for people who dont or people who have a problem just swallowing stuff like I dont take big handfuls of vitamins too, I feel good about that, having a little bit of it dissolved in the water ahead of time is actually just easier going down. It can be less nauseating. Zak That makes sense. Another related question is from Alexander whos curious about the notion of supplements cycling. What supplements do you take every day Which ones get cycled How often That relates to adrenal fatigue, right, with different substances or supplements.

That you may be taking. Do you cycle your supplements Dave Were not robots. Taking the same supplements every single day forever is something that maybe new supplement users might do. There are some supplements that I do take pretty much every day but theres a bunch of them that I dont every single day. Over time, Id become much more open about that. At the beginning of this 10, 15 years ago, I was like, Okay, heres my spreadsheet. Heres Im actually going to make this pack because I usually just A whole two weeks or whole months worth. Id.

Get this Monday through Friday when I was younger. Id be like just like old people, pill things. Im put my little vitamins in there and Id count them all up. What I found just from doing research is that vitamins interact with air. They interact with light and interact with each other. That isnt really the ideal way to do it. The other thing is that your requirements for vitamins, they change every day. Some days, you need more vitamin C. Heres an example. Lets say that you have the amount of vitamin C you can absorb.

And you can tell this with a really cool test. Its called the bowel tolerance test. You just keep taking vitamin C until you get disaster pants. Thats your number. Thats as much vitamin C as you could need but heres the problem. Get on an airplane and fly somewhere and take twice that amount and you probably could abuse it. You start getting cold. Your ability to take vitamin C will drop dramatically. Vitamin C only works Its actually a very, very steep doseresponse curve. You need to get really close to bowel tolerance.

For vitamin C to work. Years ago when I was just finishing, 15 years of sinus infections, I had these terrible things like every month that Id get when I go on antibiotics. I swore like Im done with this. Im not going to take antibiotics anymore. I had a really strong sinus infection. I went to a local physician. I said, Look, Im not going to do it. Im going to work with. Hes an alternative functional medicine guy. We did 100 grams of vitamin C intravenously. 100 grams is 100 large vitamin C dose. Intravenous vitamin C is more potent.

Than taking oral. On top of that, it took 75 grams of vitamin C capsules, thats 75 large capsules to try and reach bowel tolerance. I couldnt do it. I went back the next day and I did another 100 grams of vitamin C intravenously and another 75 grams, extra 75 grams throughout the day. I still didnt reach bowel tolerance. The sinus infection did start to get better though. Those ones were really bad, thats really the bad ones I had before I did some other protocols that helped me with it. How much.

Vitamin C should you take every day Are you sick Are you stressed The same goes for things like adrenal glandulars. I take those things anytime I got less sleep than I wanted, anytime Im traveling, anytime I got any sort of jetlag issues where Im going to be doing something that might make me want to be more resilient than normal but there are good studies that show antioxidant enzyme while its in the body are really important. If you take antioxidants all the time, you can suppress your antioxidant enzymes.

The short answer here is what I do today is I have I know you guys arent going to see this and Im not going to show it to you. Ill tell you why. I have a shelf this wide. This part of the shelf is stuff I take in the morning. The others, unfair advantage and theres some other things that you would expect to be there, some of my stuff. Theres stuff I take with meals. Its a bunch of stuff that are absorbed best with food. Then, theres stuff I take before bed. Those are the three categories.

Some of the stuff that I take with meals, I also take when I wake up and before bed but I have a little part for that. The way my brain works, Im very spatial in things. I just know this part of the shelf is where I go. I know what everything does. I really encourage you. If youre serious about biohacking, its know why youre taking your supplements, think about the day that you had yesterday and think about the day youre planning today and take the supplements that will increase your performance or increase your resilience.

Thats literally what I do. The more you do that, the more connected youll be with why youre taking these things and what they do for you. When I travel, Id pick what Im going to be doing and Id say, All right. This is an intense trip. Im going to be jetlagged. Then, I put extra stuff. For instance, on this trip, I have three bags for every day. Theres a bag of items in the morning, bag of items for one meal and a bag of items before going to sleep and a little bag, these little.

Crap bags. Every one of them has 4 grams of vitamin C in a time release form. Im taking 12 grams vitamin C a day because this is a relatively intense trip. In 10 days, Im going to three cities and Im pretty much on 12 to 14 hours a day with interviews, with recording this. Ive been on Fox News on this trip and Ill be on stage in front of 100 health people later today at JJ Virgins event. This is an intense time. That means I want to up my vitamin C. What was the answer youre looking for How should you cycle.

It Dont cycle like a robot. Cycle like someone who knows what you did yesterday and know whats happening tomorrow. When you do that, youll say, You know, this was a stressful day. Maybe Ill take more of my coenzyme, make it B complex. Thats a healthy thing to do. If you just dont feel like taking it and you would rather go meh, just dont take it that day. Its okay. Youre not a good person if you take your vitamins every day. Youre not a bad person if you dont. Those vitamins.

Are there for you. You can use them to make your day better. Thats a long answer. Zak It was. Great. I have two followups. One, for beginners who arent as in tune or aware of what all those vitamins do and its a little overwhelming to start, do you recommend any of those blood test that can be like a nutrition profile, say, when youre low on vitamin D, things like that Thats the first question. Dave Red blood cell mineral analysis can be really good. They can tell you whats.

There. They can also look at whats going on with your fatty acids in your red blood cells which should be interesting like shocking. People think too much fish oil. It will disregulate your cell membrane if you have too much fish oil. Im a fan of fish oil and all that stuff but if you take masses of it, shortterm, it can actually really help with inflammation. If you take mass of it longterm, it can actually trigger problems. Yes. Getting a quantifiable test to see your B vitamin levels is also.

Really, really useful. Totally spend money on test if you knew and youre willing to spend money on test but if you dont have the money to spend on tests, thats okay. What you do is you take the list on the website, well put it in the show notes, the 10 most important vitamins. Its pretty likely youre magnesium deficient. Taking magnesium is a really good thing and its very affordable, vitamin D, affordable, vitamin K2, not that affordable but really, really critical to keeping your calcium where you want it.

These are things that pretty much everyone should do. The reason that Im not going to tell everyone, Heres whats on my shelf, is that I weigh 300 pounds. I had toxic mold exposure. I had chronic fatigue syndrome. I had fibromyalgia. I have arthritis when I was 14. I have a unique genetic profile. I have, lets see, I dont methylate vitamins very well. If I write that whole list of everything I do for all the reasons I do it, it is so customized after nearly 20 years of customizing my stack that people out there who will go and copy.

What I do and it wont work. You need to build the things that support your biology. Thats why the Bulletproof Diet is a roadmap and a spectrum with three tools that tell you heres how to navigate the roadmap to get what works best for you because youre not that person if you enjoy white potatoes without peels. Youre just not assuming that youre genetically okay with it. They make me itch and cause me joint pain. Thats why theyre a suspect food. The same thing is true with vitamins. One of the things I.

Did early on with B6 B6 is good for you. Theres a problem with that. Excessive B6 is tied to peripheral neuropathy which means numbness and tingling in your fingers and toes. I actually got this from excessive B6 a long time ago. If you dont catch it in time, you keep taking B6, it can be permanent. It actually makes me a little bit scared when I see supplement companies just including vitamin B6 all willynilly because everyone knows its good for you. If youre taking five different things and all of them had a bunch of B6 on them, you could have problems.

There. Be aware of the toll you take from different vitamins as well. Bottom line is theres a science of supplementing. I recommend blood tests but dont do it just because I do it. Do it because your body and your day and your diet and exercise and the amount of sleep you get, the amount of stress youre under, those dictate what you do. Be quantitative with the blood test if you can afford it. If not, go down the list with cost benefit analysis. Thats why the top 10 Bulletproof supplements are there.

Zak My second followup question on that is something that I know is in a lot of peoples minds. Why does everything that we talked about biohacking and stuff cause disaster pants Its like weve mentioned different ways you can get disaster pants already on this podcast. Is that Dave Why does everything cause disaster pants Zak Too much MCT, too much vitamin C. Dave Its true. Your body is good at absorbing stuff. It will absorb so much but its not that good at it. One of the reasons that I do intravenous nutrition on occasion, probably.

Every time I go on a long trip, when I come back If I can arrange it with local people where I live or sometimes, Ill just stop by in New York and Ill see someone who does intravenous vitamins. The reason I do that is that your gut can only absorb so quickly. If you want to get extra vitamin C into the body beyond what the gut can absorb, youll do it. Heres what happens. Because I wanted to bring this in, I brought it as much as I could.

Do and what do I do with whats left You push it down. If its irritating and the gut wasnt designed for basically the large intestine to have this present in it, the bodys like, Oh, its in the large intestine and it shouldnt be. Lets get it out of there. Thus, disaster pants. Its funny. Its one of the ways the body eliminates too much of something. Things like MCT oil, you absorb it. The body loves MCT oil. It goes through very quickly. It will escort other things through which is really, really cool. In fact, heres.

A cool study we havent talked about yet. Theres a study from the top of my mind. I dont remember where it was done but they looked at using whats in brain octane or XCT oil with cayenne and found a 50 increase in thermogenesis which is cool because cayenne itself can cause thermogenesis, brain octane and XCT oil can cause thermogenesis. You put those things together. Why, because the oil helps the cayenne to come in. Now, I would caution you cayenne is on the list of suspect foods for two reasons. Its.

One of the highest aflatoxin harboring spices. 85 of people with Crohns disease have aflatoxin present in their blood at higher levels. Thats an interesting other study. You might want to avoid it for that reason. Also, its a nightshade. If youre sensitive to nightshades, you can get autoimmune reactions from them. Take cayenne because it kicks ass and take it with brain octane if you want to kick even more ass. Its a great nuance but if you take too much of it and youre not only going to have disaster pants. Youre.

Going to have hot disaster pants. Thats even worse. Watch out. Zak Disaster pants is your bodys own way of quantifying what we can Dave Its a strong signal that says dont do that much again. Zak Andy Hnilo talked about putting cayenne in his Bulletproof coffee and taking it up a notch. I tried that. Oh my gosh. Dave Ive done it too. Man, you sweat when you do it. It doesnt taste good though is the problem. I dont appreciate it. Zak I like it actually. Dave Do you.

Zak Yeah. Dave I like it more in the hot chocolate kind of thing. Zak Thats really Dave Thats more of a Mexican thing. Zak Cool. That is going to wrap up part one of this Q and A podcast. Well be back probably later this week within the week with part two. Dave Awesome. Hey, thanks Zak. Zak Thank you. Technology Upgraded XCT Oil Brain Octane Oil Upgraded Coffee Upgraded Collagen Protein Upgraded Whey Protein Sole Salt Crystals Natural Calm Magnesium Vitamin C Vitamin D3 Vitamin K2 Krill Oil.

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