Peripheral Nerve Degeneration

Canadian scientists have discovered a way to turn a simple blood sample from a man or woman into a variety of nerve cells, including those that are responsible for pain, numbness and other sensations. This technology will allow researchers to test potential drugs for treating pain using the nerve cells in a lab, all based on an individual patient’s own genetic signature, says Mick Bhatia, who led the team of researchers at McMaster University in Hamilton. Now we can take easy to obtain blood samples and make the main cell types of neurological.

Systems the central nervous system and the peripheral nervous system in a dish that is specialized for each patient. According to Mick Bhatia, Nobody has ever done this with adult blood, ever Up until now, there has been no good way to get access to human neural cells to test or study. While researchers can buy certain kinds of rat neural cell lines, they don’t consistently respond the way human neural cells do. The new technique involves extracting stem cells from blood ones that normally have the potential to become red blood cells or various kinds.

Of white blood cells involved in fighting off pathogens. The blood stem cells are converted over about a month into neural stem cells using a patented technique. Those cells can survive for several months in a petri dish. These neural stem cells are then manipulated in the lab to give rise to several types of nerve cells, including those that make up the peripheral nervous system throughout the arms, legs and the rest of the body. We can actually take a patient’s blood sample, as routinely performed in a doctor’s office,.

Blood turned into nerve cells by Canadian researchers.

And with it we can produce one million sensory neurons. We can also make central nervous system cells. The researchers hope to discover new pain drugs that take aim only at the peripheral nerve system, while not affecting the brain and the rest of the central nervous system. You don’t want to feel sleepy or unaware, you just want your pain to go away, says Bhatia. His lab hopes to further develop the bloodgenerated neural stem cells into motor and other kinds of neurons that could conceivably one day be transplanted into patients to restore healthy.

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