Hot off the press news about knee arthritis from Madrid not all knee pain comes from the knee Neuropathic pain features common in knee OA Lucy Piper writing in Medwire News reported enough patients with knee osteoarthritis OA experience pain with neuropathic characteristics to warrant attempts to diagnose and classify these features, say researchers. They found that among 2176 patients with OA, a third scored positively for neuropathic pain on the Douler Neuropathique DN4 questionnaire, after patients with reasons other than OA for such pain had been excluded. Analysis showed that three of these potential confounders conditions other than OA that.
Cause changes in cutaneous sensory perceptions on the knee, or cause abnormal sensations over the area of the knee, and referred back or hip pain were highly specific for neuropathic pain, but less sensitive than the DN4. When these factors are absent, the presence of neuropathic pain is unlikely, yet the DN4 can sense additional neuropathic features in some patients, explain the researchers, led by ngel Oteolvaro Hospital General Universitario Gregorio Maran, Madrid, Spain. Further confirmation and classification of these additional features could reveal links between neuropathophysiology and signs and symptoms of the condition, they note.